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Nitrofurantoin jaundice — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentNitrofurantoin jaundiceGPhC CRA

A woman on long-term nitrofurantoin prophylaxis develops jaundice, dark urine and fatigue. What monitoring is required?

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Correct answer: D — Urgent liver function assessment and medicine review

This scenario assesses Nitrofurantoin jaundice in a UK pharmacy practice context. Nitrofurantoin can rarely cause hepatic injury, and jaundice requires urgent review. The best answer is Urgent liver function assessment and medicine review because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment