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Indapamide and hyponatraemia risk — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsIndapamide and hyponatraemia riskGPhC CRA

A 70-year-old woman starts indapamide and has previous hyponatraemia. She also takes sertraline. What monitoring is required?

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Correct answer: E — Urea and electrolytes after initiation

This scenario assesses Indapamide and hyponatraemia risk in a UK pharmacy practice context. Thiazide-like diuretics can cause hyponatraemia and hypokalaemia, especially in older adults and those on SSRIs. The best answer is Urea and electrolytes after initiation because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; NICE CKS