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Gabapentin with opioid COPD — GPhC CRA MCQ

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EasyCNS TherapeuticsGabapentin with opioid COPDGPhC CRA

An older man with COPD on morphine becomes very sleepy after gabapentin dose increase. What is the most appropriate action?

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Correct answer: B — Contact the prescriber because respiratory depression risk is increased

This scenario assesses Gabapentin with opioid COPD in a UK pharmacy practice context. Gabapentin with opioids and respiratory disease increases sedation and respiratory depression risk. The best answer is Contact the prescriber because respiratory depression risk is increased because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; MHRA Drug Safety Update