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Methotrexate warning symptoms — GPhC CRA MCQ

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EasyPatient Counselling and Pharmaceutical CareMethotrexate warning symptomsGPhC CRA

A patient collecting methotrexate and folic acid for the first time asks what side effects matter. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Report sore throat, mouth ulcers, bruising or breathlessness promptly

This scenario assesses Methotrexate warning symptoms in a UK pharmacy practice context. These symptoms can indicate methotrexate blood, infection or lung toxicity. The best answer is Report sore throat, mouth ulcers, bruising or breathlessness promptly because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; MEP