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Gabapentin renal dose — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentGabapentin renal doseGPhC CRA

A woman with eGFR 21 is prescribed gabapentin 600 mg three times daily and has recent falls. What is the most appropriate alternative?

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Correct answer: A — Query the gabapentin dose because renal adjustment may be needed

This scenario assesses Gabapentin renal dose in a UK pharmacy practice context. Gabapentin is renally cleared and high exposure increases dizziness, sedation and falls. The best answer is Query the gabapentin dose because renal adjustment may be needed because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF