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Methotrexate label — GPhC CRA MCQ

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ModerateDispensing and SupplyMethotrexate labelGPhC CRA

A methotrexate prescription says 15 mg once weekly but the generated label says take as directed. What is the legal classification/requirement?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Change the label to clear weekly dosing before supply

This scenario assesses Methotrexate label in a UK pharmacy practice context. Methotrexate weekly dosing errors can be fatal and require explicit labelling. The best answer is Change the label to clear weekly dosing before supply because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; MEP