skip to main content

Citalopram and clarithromycin — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCNS TherapeuticsCitalopram and clarithromycinGPhC CRA

An older woman taking citalopram 40 mg with previous prolonged QT is prescribed clarithromycin. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Additive QT prolongation and arrhythmia risk

This scenario assesses Citalopram and clarithromycin in a UK pharmacy practice context. Citalopram and clarithromycin can both prolong QT interval, especially in older patients or with prior QT prolongation. The best answer is Additive QT prolongation and arrhythmia risk because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF