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ACE inhibitor in pregnancy — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsACE inhibitor in pregnancyGPhC CRA

A 31-year-old woman collecting ramipril 5 mg daily says she has a positive pregnancy test. She asks whether to continue until her routine GP appointment. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Withhold ramipril and contact the prescriber urgently

This scenario assesses ACE inhibitor in pregnancy in a UK pharmacy practice context. ACE inhibitors should be stopped in pregnancy and replaced with a pregnancy-appropriate antihypertensive after urgent review. The best answer is Withhold ramipril and contact the prescriber urgently because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; NICE CKS