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St John’s wort COC — GPhC CRA MCQ

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HardDrug InteractionsSt John’s wort COCGPhC CRA

A woman taking a combined oral contraceptive wants St John’s wort for low mood. What is the most important interaction to flag?

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Correct answer: E — Reduced contraceptive effectiveness

This scenario assesses St John’s wort COC in a UK pharmacy practice context. St John’s wort induces enzymes and can reduce hormonal contraceptive effectiveness. The best answer is Reduced contraceptive effectiveness because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; MEP