Carbamazepine apixaban — GPhC CRA MCQ
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Correct answer: E — Reduced apixaban exposure and anticoagulant effect
This scenario assesses Carbamazepine apixaban in a UK pharmacy practice context. Carbamazepine is an enzyme inducer and can reduce DOAC exposure. The best answer is Reduced apixaban exposure and anticoagulant effect because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.
Reference: BNF