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Clozapine sore throat — GPhC CRA MCQ

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ModerateCNS TherapeuticsClozapine sore throatGPhC CRA

A man taking clozapine presents with fever, sore throat and mouth ulcers. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Withhold supply and arrange urgent blood count assessment

This scenario assesses Clozapine sore throat in a UK pharmacy practice context. Clozapine can cause neutropenia or agranulocytosis presenting with infection symptoms. The best answer is Withhold supply and arrange urgent blood count assessment because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF