Tramadol sertraline — GPhC CRA MCQ
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Correct answer: A — Serotonin syndrome and seizure risk
This scenario assesses Tramadol sertraline in a UK pharmacy practice context. Tramadol has serotonergic activity and lowers seizure threshold, increasing risk with SSRIs. The best answer is Serotonin syndrome and seizure risk because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.
Reference: BNF