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ACE inhibitor cough — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsACE inhibitor coughGPhC CRA

A 58-year-old woman develops a persistent dry cough six weeks after starting ramipril for hypertension. Her blood pressure is controlled. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CSwitch to an angiotensin-II receptor blocker after prescriber review

This scenario assesses ACE inhibitor cough in a UK pharmacy practice context. A persistent dry cough is a recognised ACE inhibitor adverse effect, and an ARB is a usual alternative when clinically suitable. The best answer is Switch to an angiotensin-II receptor blocker after prescriber review because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; NICE CKS