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Amitriptyline frailty falls — GPhC CRA MCQ

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ModerateCNS TherapeuticsAmitriptyline frailty fallsGPhC CRA

An older woman with recurrent falls develops confusion and dry mouth after amitriptyline, and the dose is being increased. What is the most appropriate action?

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Correct answer: E — Query the dose increase because anticholinergic harm is likely

This scenario assesses Amitriptyline frailty falls in a UK pharmacy practice context. Amitriptyline is anticholinergic and sedating, increasing confusion and falls risk in older adults. The best answer is Query the dose increase because anticholinergic harm is likely because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; NICE CKS