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Lithium and NSAID — GPhC CRA MCQ

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ModerateDrug InteractionsLithium and NSAIDGPhC CRA

A patient on lithium asks to buy ibuprofen for a sprained ankle. She has no recent lithium level available. What is the most important interaction to flag?

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Correct answer: C — NSAIDs can increase lithium levels and toxicity risk

NSAIDs can reduce renal lithium clearance and increase lithium concentrations. The patient should avoid unsupervised NSAID use and seek advice on safer analgesia. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF