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Febuxostat cardiovascular risk — GPhC CRA MCQ

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HardMusculoskeletal TherapeuticsFebuxostat cardiovascular riskGPhC CRA

A patient with gout and previous myocardial infarction asks about switching from allopurinol to febuxostat because a friend found it easier. What is the most appropriate action?

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Correct answer: B — Refer to the prescriber because cardiovascular history affects urate-lowering choice

Febuxostat may require caution in patients with major cardiovascular disease depending on current guidance and individual risk. Urate-lowering therapy changes should be made by the prescriber after reviewing history, urate levels and previous tolerance. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF; NICE CKS