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Lithium toxicity — GPhC CRA MCQ

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HardCNS TherapeuticsLithium toxicityGPhC CRA

A patient on lithium presents with coarse tremor, diarrhoea, vomiting and unsteady gait. She recently started bendroflumethiazide for hypertension. What is the most appropriate action?

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Correct answer: D — Refer urgently for lithium level, renal function and clinical assessment

Coarse tremor, gastrointestinal upset and ataxia suggest lithium toxicity. Thiazide diuretics and dehydration can increase lithium concentrations, making urgent assessment necessary. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF; NICE CKS