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ACE inhibitor and potassium salt substitute — GPhC CRA MCQ

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EasyDrug InteractionsACE inhibitor and potassium salt substituteGPhC CRA

A patient taking ramipril and spironolactone asks about using a low-sodium salt substitute after reading about blood pressure diets. What is the most important interaction to flag?

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Correct answer: ASalt substitutes may contain potassium and increase hyperkalaemia risk

Many low-sodium salt substitutes contain potassium chloride. In a patient taking an ACE inhibitor and spironolactone, additional potassium can increase hyperkalaemia risk. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF