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Methotrexate weekly dosing — GPhC CRA MCQ

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EasyMusculoskeletal TherapeuticsMethotrexate weekly dosingGPhC CRA

A prescription for methotrexate 10 mg is issued with directions stating take daily. The patient has rheumatoid arthritis and usually takes it on Mondays. What is the most appropriate action?

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Correct answer: A — Do not dispense until the prescriber confirms the intended weekly dose

Methotrexate for rheumatoid arthritis is normally taken once weekly, and daily dosing errors can be fatal. A prescription stating daily must be urgently clarified before supply. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF; MEP