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DOAC renal review — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentDOAC renal reviewGPhC CRA

A patient on dabigatran for atrial fibrillation has an acute decline in renal function during admission. The discharge prescription continues the same dose. What is the most appropriate action?

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Correct answer: B — Query anticoagulant dose and suitability in light of renal function

Dabigatran is substantially renally cleared, so renal impairment can increase bleeding risk. Acute changes in renal function should prompt review of dose and suitability. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF