skip to main content

Fluoroquinolone tendon risk — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateAdverse Drug Reactions and Drug SafetyFluoroquinolone tendon riskGPhC CRA

An older patient prescribed ciprofloxacin for prostatitis develops Achilles tendon pain after 3 days. He also takes prednisolone. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Advise stopping ciprofloxacin and seeking urgent prescriber advice

Fluoroquinolones can cause tendinitis and tendon rupture, with higher risk in older adults and those taking corticosteroids. Tendon pain should prompt stopping the fluoroquinolone and urgent medical advice unless the prescriber advises otherwise. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: MHRA Drug Safety Update; BNF