Lamotrigine rash — GPhC CRA MCQ
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Correct answer: E — Refer urgently for assessment and advise not to take further doses until reviewed
Lamotrigine can rarely cause serious skin reactions, especially when rash is accompanied by fever or mucosal involvement. Urgent review is required because continuing treatment may worsen a potentially life-threatening reaction. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.
Reference: BNF