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ACE inhibitor initiation — GPhC CRA MCQ

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EasyCardiovascular TherapeuticsACE inhibitor initiationGPhC CRA

A 59-year-old man has been newly prescribed ramipril 2.5 mg daily for hypertension. He asks when his blood tests need checking after starting treatment. What monitoring is required?

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Correct answer: C — Check renal function and serum potassium within 1 to 2 weeks

ACE inhibitors can reduce glomerular filtration pressure and increase serum potassium, particularly in renal impairment or dehydration. Baseline renal function and potassium should be reviewed, then repeated shortly after initiation or dose increase. Liver function and thyroid function are not routine safety checks for ramipril. Delayed annual review would miss early renal deterioration or hyperkalaemia.

Reference: BNF; NICE CKS