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Azathioprine pancreatitis — GPhC CRA MCQ

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HardGastro-intestinal TherapeuticsAzathioprine pancreatitisGPhC CRA

A patient with Crohn's disease started azathioprine 3 weeks ago and now has severe upper abdominal pain radiating to the back with vomiting. What is the most appropriate action?

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Correct answer: C — Refer urgently for assessment of possible azathioprine-induced pancreatitis

Azathioprine can cause pancreatitis, especially early in treatment. Severe epigastric pain radiating to the back with vomiting requires urgent assessment. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF