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Antidepressant in pregnancy — GPhC CRA MCQ

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ModerateCNS TherapeuticsAntidepressant in pregnancyGPhC CRA

A woman taking sertraline for recurrent depression tells you she is planning pregnancy and is worried about medication risk. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Advise discussion with her GP or specialist before making changes

Antidepressant treatment around pregnancy requires an individual risk-benefit discussion. Abrupt discontinuation can cause withdrawal symptoms and relapse, while St John's wort has important interaction and safety concerns. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: BNF; NICE CKS