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H. pylori eradication — GPhC CRA MCQ

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ModerateGastro-intestinal TherapeuticsH. pylori eradicationGPhC CRA

A patient is prescribed omeprazole, amoxicillin and clarithromycin for H. pylori eradication. She asks why three medicines are needed. What would you advise the patient?

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Correct answer: CExplain the PPI and two antibiotics improve eradication rates

H. pylori eradication regimens use acid suppression plus two antibiotics to improve bacterial eradication and reduce resistance risk. The course should be taken as prescribed even if symptoms improve. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: NICE CKS; BNF