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Digoxin and amiodarone — GPhC CRA MCQ

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HardDrug InteractionsDigoxin and amiodaroneGPhC CRA

A patient taking digoxin for atrial fibrillation is started on amiodarone. He later reports nausea and visual disturbance. What is the most important interaction to flag?

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Correct answer: D — Amiodarone can increase digoxin concentration and toxicity risk

Amiodarone can increase digoxin levels and both medicines can slow heart rate. Nausea and visual disturbance suggest possible digoxin toxicity requiring review. The other options either delay appropriate care, use an unsuitable medicine, or miss the main safety issue.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-65