skip to main content

Verapamil and beta-blocker — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardCardiovascular TherapeuticsVerapamil and beta-blockerGPhC CRA

A prescription for verapamil modified-release is received for a patient already taking bisoprolol for angina. The patient has a resting pulse of 54 beats per minute. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Additive bradycardia and heart block risk

Verapamil and beta-blockers both slow atrioventricular conduction and reduce heart rate. Combined use can precipitate severe bradycardia, heart block or heart failure, particularly in patients with a low resting pulse. The prescription should be queried before supply. The interaction is pharmacodynamic rather than an absorption problem.

Reference: BNF