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Phaeochromocytoma — SCE Endocrinology MCQ

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HardAdrenalPhaeochromocytomaSCE Endocrinology

A man with a secretory phaeochromocytoma is scheduled for adrenalectomy. Which UK preparation package is most appropriate?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Use preoperative alpha blockade and volume expansion, adding beta blockade later

Explanation lettering: C = shown as B · B = shown as C · E = shown as D · D = shown as E

E is correct. UK Society for Endocrinology guidance starts alpha blockade at least 14 days preoperatively; phenoxybenzamine often begins 10 mg once or twice daily and is titrated, with salt and fluid expansion. A beta blocker may be added for tachycardia only after effective alpha blockade, typically no earlier than four days, to avoid unopposed vasoconstriction. Same-day preparation, sodium restriction, beta-first therapy and unprepared surgery risk crisis.

Reference: https://www.endocrinology.org/media/2711/ppgl-updated-2018.pdf