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Thyroid nodule — SCE Endocrinology MCQ

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ModerateThyroidThyroid noduleSCE Endocrinology

A 45-year-old man has a 2.5 cm thyroid nodule. Ultrasound shows microcalcifications, irregular margins and taller-than-wide shape. TSH is normal. What is the most appropriate next investigation?

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Correct answer: A — Ultrasound-guided fine-needle aspiration

Suspicious ultrasound features in a thyroid nodule warrant fine-needle aspiration. Levothyroxine suppression is not appropriate nodule therapy. Thyroglobulin is mainly used in follow-up of differentiated thyroid cancer, not primary diagnosis of a nodule.

Reference: British Thyroid Association Guidelines; NICE NG145