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Type 2 diabetes with heart failure — SCE Endocrinology MCQ

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EasyDiabetesType 2 diabetes with heart failureSCE Endocrinology

A 57-year-old woman with type 2 diabetes has heart failure with reduced ejection fraction and HbA1c 64 mmol/mol. eGFR is 55 ml/min/1.73 m2. She is taking gliclazide but no metformin because of previous intolerance. What is the most appropriate glucose-lowering treatment change?

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Correct answer: AIntroduce an SGLT2 inhibitor

SGLT2 inhibitors provide heart failure benefit and are favoured in this phenotype. Pioglitazone can worsen fluid retention and is a poor choice in heart failure. Increasing sulfonylurea may reduce HbA1c but does not provide the same heart failure protection.

Reference: NICE NG28; NICE NG106; BNF