skip to main content

Autoimmune comorbidity in type 1 diabetes — SCE Endocrinology MCQ

Instant feedback + full explanation. One question, done properly.

EasyDiabetesAutoimmune comorbidity in type 1 diabetesSCE Endocrinology

A 31-year-old woman with type 1 diabetes has coeliac disease symptoms and iron deficiency. Tissue transglutaminase IgA is positive. She asks why these conditions occur together. What is the underlying pathophysiology?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Shared autoimmune predisposition

Type 1 diabetes is associated with other autoimmune conditions including coeliac disease and autoimmune thyroid disease. Insulin does not damage intestinal villi. The pearl is that persistent gastrointestinal symptoms or unexplained iron deficiency in type 1 diabetes should prompt coeliac testing.

Reference: NICE NG17; NICE Coeliac Disease Guidance