skip to main content

Myxoedema coma — SCE Endocrinology MCQ

Instant feedback + full explanation. One question, done properly.

EasyEndocrine emergencies/dynamic testsMyxoedema comaSCE Endocrinology

A 73-year-old woman has myxoedema coma. She is hypothermic, bradycardic and hyponatraemic. Random cortisol is pending. What is the most appropriate immediate endocrine treatment sequence?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Give hydrocortisone then thyroid hormone replacement

Hydrocortisone should be given before thyroid hormone in myxoedema coma until adrenal insufficiency is excluded. Thyroid hormone can increase cortisol clearance and precipitate adrenal crisis. Supportive critical care is also essential.

Reference: Society for Endocrinology Emergency Guidance; BNF