Graves' disease in pregnancy — SCE Endocrinology MCQ

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EasyEndocrinology in pregnancyGraves' disease in pregnancySCE Endocrinology

A 28-year-old woman is 9 weeks pregnant with Graves' disease. She has tremor, weight loss, TSH <0.01 mU/L and free T4 35 pmol/L. She is not taking medication. What is the most appropriate management?

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Correct answer: B — Start propylthiouracil and monitor thyroid function closely

Propylthiouracil is generally preferred in the first trimester for overt Graves' hyperthyroidism. Radioiodine is contraindicated in pregnancy. Untreated overt thyrotoxicosis increases maternal and fetal risks.

Reference: NICE NG145; BNF