Thyroid assay interference — SCE Endocrinology MCQ
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Correct answer: A — Repeat thyroid tests when clinically stable and review assay interference
Discordant thyroid tests in an unwell patient should prompt repeat testing and consideration of assay artefact, including heparin-related free fatty acid effects. Treating as Graves' disease without suppressed TSH or clinical support is inappropriate. The pearl is that thyroid tests should be interpreted with the clinical context.
Reference: Association for Clinical Biochemistry Guidance; NICE NG145