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Peri-operative adrenal insufficiency — SCE Endocrinology MCQ

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ModerateAdrenalPeri-operative adrenal insufficiencySCE Endocrinology

A 52-year-old man with Addison's disease is having colectomy. He takes hydrocortisone 10 mg morning, 5 mg lunchtime and fludrocortisone 100 micrograms daily. What is the most appropriate peri-operative steroid plan?

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Correct answer: EParenteral stress-dose hydrocortisone during major surgery

Major surgery requires stress-dose parenteral hydrocortisone in adrenal insufficiency. Usual oral dosing is inadequate during surgical stress and fasting. Mineralocorticoid replacement may be covered by high-dose hydrocortisone temporarily, but specialist protocols should guide care.

Reference: Society for Endocrinology Steroid Emergency Card Guidance; NICE NG243