skip to main content

SGLT2 sick-day management — SCE Endocrinology MCQ

Instant feedback + full explanation. One question, done properly.

EasyDiabetesSGLT2 sick-day managementSCE Endocrinology

A 65-year-old man with type 2 diabetes and chronic kidney disease has HbA1c 57 mmol/mol. He has repeated urinary tract infections and takes dapagliflozin. He develops fever, flank pain and hypotension. What is the most appropriate medication action during this illness?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Temporarily withhold dapagliflozin and assess ketones and renal function

SGLT2 inhibitors should be withheld during serious acute illness because of dehydration and ketoacidosis risk. Doubling the dose is unsafe and does not treat infection. Sick-day rules are an essential part of SGLT2 prescribing.

Reference: NICE NG28; BNF