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Severe falciparum malaria — SCE Acute Medicine MCQ

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HardSepsis and Infectious EmergenciesSevere falciparum malariaSCE Acute Medicine

A 41-year-old woman is assessed on the acute medical unit. She has falciparum parasitaemia of 8%, confusion and acute kidney injury after travel to Ghana. Platelets are low and lactate is raised. Initial assessment includes relevant observations, bedside tests and urgent blood results. What is the most appropriate next step in management?

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Correct answer: DStart intravenous artesunate urgently

Start intravenous artesunate urgently is the best answer because severe falciparum malaria requires urgent parenteral artesunate and critical care involvement. Insert a large-bore chest drain using image guidance is plausible, but it is less appropriate for the physiology or timing described in this stem. The other distractors either fit a neighbouring presentation, delay definitive treatment, or miss the key immediate risk. Clinical pearl: High parasitaemia, organ dysfunction or impaired consciousness define severe disease.

Reference: UK malaria treatment guidelines