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Morphine renal impairment — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentMorphine renal impairmentGPhC CRA

A 70 kg adult with acute DVT has Cockcroft–Gault creatinine clearance 22 mL/min. Which renal-adjusted enoxaparin treatment regimen should be checked?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Enoxaparin 70 mg subcutaneously once daily

For acute VTE treatment in severe renal impairment, the renal-adjusted regimen is 1 mg/kg once daily. At 70 kg this is 70 mg once daily. The indication, actual body weight, bleeding risk and any local anti-Xa policy must still be confirmed.

Reference: BNF: enoxaparin sodium: https://bnf.nice.org.uk/drugs/enoxaparin-sodium/