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Potassium supplement with ACE inhibitor — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsPotassium supplement with ACE inhibitorGPhC CRA

A patient on ramipril asks to buy potassium supplements for leg cramps. They have chronic kidney disease stage 3 documented on the PMR. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Hyperkalaemia risk requiring pharmacist referral

ACE inhibitors and kidney disease both increase hyperkalaemia risk. Potassium supplementation should not be supplied without clinical review. In this scenario, the correct option is hyperkalaemia risk requiring pharmacist referral. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-60