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Clozapine infection warning — GPhC CRA MCQ

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HardCNS TherapeuticsClozapine infection warningGPhC CRA

A patient taking clozapine presents with sore throat, fever and mouth ulcers. They asks for throat lozenges. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Urgent full blood count and clozapine service advice

Clozapine can cause neutropenia and agranulocytosis. Fever or sore throat requires urgent blood count assessment and specialist advice. In this scenario, the correct option is urgent full blood count and clozapine service advice. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-59