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SGLT2 sick-day advice — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsSGLT2 sick-day adviceGPhC CRA

A patient taking dapagliflozin develops vomiting and poor oral intake. They ask whether to continue diabetes tablets until the GP appointment. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Temporarily withhold dapagliflozin and seek clinical advice

SGLT2 inhibitors should be withheld during acute illness with dehydration risk because of euglycaemic ketoacidosis risk. The patient needs sick-day advice and safety-netting. In this scenario, the correct option is temporarily withhold dapagliflozin and seek clinical advice. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; NICE CKS