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PPI step-down — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsPPI step-downGPhC CRA

A patient has taken omeprazole 20 mg daily for dyspepsia for six months and is symptom-free. They ask whether to continue indefinitely. What is the most appropriate action?

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Correct answer: B — Discuss step-down or review if long-term treatment is not indicated

PPIs are useful but long-term use should be periodically reviewed. Step-down, intermittent treatment or stopping may be appropriate depending on indication. In this scenario, the correct option is discuss step-down or review if long-term treatment is not indicated. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; NICE CKS