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Digoxin and verapamil — GPhC CRA MCQ

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HardDrug InteractionsDigoxin and verapamilGPhC CRA

A patient taking digoxin is started on verapamil for rate control. They have nausea and a slow pulse today. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AIncreased digoxin concentration and bradycardia risk

Verapamil can increase digoxin concentrations and also slows AV conduction. Symptoms and bradycardia make the interaction clinically urgent. In this scenario, the correct option is increased digoxin concentration and bradycardia risk. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; Stockley's Drug Interactions