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NSAID cirrhosis — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentNSAID cirrhosisGPhC CRA

A patient with cirrhosis and ascites asks to buy ibuprofen for ankle pain. They are taking spironolactone and furosemide. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Avoid NSAID and refer for safer analgesia

NSAIDs can precipitate renal impairment, gastrointestinal bleeding and fluid retention in cirrhosis. Safer analgesia requires careful assessment. In this scenario, the correct option is avoid NSAID and refer for safer analgesia. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; NICE CKS