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Flucloxacillin administration — GPhC CRA MCQ

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EasyInfections and AntimicrobialsFlucloxacillin administrationGPhC CRA

A patient prescribed flucloxacillin for cellulitis says they usually takes medicines with meals because of nausea. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Take flucloxacillin on an empty stomach if tolerated

Flucloxacillin absorption is reduced by food, so it is usually taken before meals. Practical counselling should balance absorption with tolerability. In this scenario, the correct option is take flucloxacillin on an empty stomach if tolerated. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF