Labelling methotrexate — GPhC CRA MCQ
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Correct answer: B — Ensure the label clearly states once weekly dosing and the day
Methotrexate daily dosing errors can be fatal. The label must make the weekly schedule explicit and the patient should be counselled. In this scenario, the correct option is ensure the label clearly states once weekly dosing and the day. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.
Reference: BNF; MHRA Drug Safety Update; MEP