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Labelling methotrexate — GPhC CRA MCQ

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EasyDispensing and SupplyLabelling methotrexateGPhC CRA

A methotrexate prescription says 10 mg once weekly, but the dispensing label template defaults to daily directions. The trainee asks whether to override. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BEnsure the label clearly states once weekly dosing and the day

Methotrexate daily dosing errors can be fatal. The label must make the weekly schedule explicit and the patient should be counselled. In this scenario, the correct option is ensure the label clearly states once weekly dosing and the day. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; MHRA Drug Safety Update; MEP