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Isotretinoin mood change — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyIsotretinoin mood changeGPhC CRA

A young adult taking isotretinoin reports low mood and thoughts that life is not worth living. They ask for moisturiser only. What is the most appropriate action?

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Correct answer: E — Escalate urgently for mental health and specialist review

Severe mood symptoms and suicidal ideation require immediate assessment. The pharmacist should not treat this as a routine dermatology adverse effect. In this scenario, the correct option is escalate urgently for mental health and specialist review. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF; MHRA Drug Safety Update