skip to main content

Lamotrigine rash — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCNS TherapeuticsLamotrigine rashGPhC CRA

A patient who started lamotrigine ten days ago reports a spreading rash and fever. They ask for an antihistamine. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Stop supply and refer urgently for medical assessment

Rash with systemic symptoms soon after lamotrigine initiation may indicate serious cutaneous adverse reactions. Urgent assessment is needed. In this scenario, the correct option is stop supply and refer urgently for medical assessment. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.

Reference: BNF