Methotrexate counselling — GPhC CRA MCQ
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Correct answer: E — Take methotrexate once weekly and seek advice for flare pain
Methotrexate dosing errors are high-risk. Patients must understand weekly dosing, folic acid instructions and when to seek help for toxicity. In this scenario, the correct option is take methotrexate once weekly and seek advice for flare pain. The other options are plausible but do not address the key clinical, legal or safety issue as directly. This aligns with UK pharmacy practice guidance cited in the reference field.
Reference: BNF; MHRA Drug Safety Update